Transplant Skin Cancer Network: Call for applications | aad.org

American Academy of Dermatology American Academy of Dermatology

Transplant Skin Cancer Network: Call for applications

The American Academy of Dermatology is seeking dermatologists to participate in an effort to study squamous cell carcinoma incidence, metastasis, and mortality among transplant recipients.

Dermatologists currently working with transplant centers to evaluate and treat patients with skin disease, including skin cancer, are encouraged to submit an application. The Academy is providing seed money and facilitating the development of a network of dermatologists paired with transplant centers that will conduct the initial study and be able to seek and secure funding from the NIH and other sources for future research.

About the transplant skin cancer study

The purpose of the network will be to conduct a multi-center, retrospective cohort study of SCC using data from transplant recipients’ medical records over a period of up to three years to measure:
  1. SCC mortality among transplant recipients overall, and as a function of time since transplant, other risk factors, and treatments or therapies.
  2. The risk of metastasis among transplant recipients with cutaneous SCC as a function of treatment, types of immunosuppressant, and time from treatment.
  3. The incidence of SCC of the skin after different types of transplant and the potential effect of prior history of SCC of the skin and various forms of immunosuppressant used to prevent transplant rejection.
  4. The effect of surveillance times by a dermatologist after transplant on various outcomes including size of SCC, type of treatment, recurrence, metastasis, and survival.
  5. Survival from date of diagnosis of cutaneous SCC and metastatic skin cancer compared to overall survival in transplant recipients.

Participant responsibilities

Dermatologist applicants are responsible for recruiting affiliated transplant centers and coordinating with the AAD’s Cutaneous Oncology Workgroup and the transplant centers to assure that the requirements of the study are met.

The lead transplant center will be responsible for coordinating the data from all participating sites and assuring that all regulatory requirements are met at all sites. The research coordinator at the lead center will assist in coordination of participating transplant center activities such as reconciliation of Institutional Review Board (IRB) protocols and consent forms, and data aggregation.

An agreement between participants will ensure dissemination of the study results is collaborative and that authorship of any resulting publications is determined prospectively.

Applications

Applications are due Oct. 30, 2013; requirements and process are summarized below.
Dermatologists applying for the lead center must:
  • Be a board-certified AAD member.
  • Supply a current curriculum vitae and a signed letter of intent, which includes acknowledgment of total amount of AAD seed funding and of the expected timeline for completion of this project. 
  • Provide a letter of support of the project by his or her dermatology department chair and/or by the Transplant Medicine division or equivalent at his or her institution. 
  • Have track record of competence, coordination, and timely completion of clinical research trials. 
  • Agree to oversight of their participation by the AAD Cutaneous Oncology Workgroup.
  • Provide — after the initial application — site-specific budget allocation, and a draft IRB protocol and informed consent.
Participating center dermatologists must:
  • Be a board-certified AAD member.
  • Be with affiliated transplant center. 
  • Manage and treat dermatologic conditions of transplant patients.
  • Provide a letter of commitment signed by the investigator and the associated transplant center.
  • Pledge support (not specifically defined) for the investigator and center's participation in this network.
  • Agree to oversight of their participation by the AAD Cutaneous Oncology Workgroup.

To apply, submit an email with required documents attached. Include the following information in your email: 

  • Your name.
  • Your AAD member ID number.
  • The name of your affiliated transplant center.