DW Insights & Inquiries


Antihypertensive agents, especially diuretics and calcium channel blockers, may cause eczematous dermatoses in older patients.

The number of cases of Yao syndrome due to mutations in NOD2 has been increasing. It should be in the differential diagnosis of patients manifesting recurrent fever, rashes, musculoskeletal, gastrointestinal, and sicca-like symptoms.

Both primary and secondary trimethylaminuria can be socially debilitating. While dietary manipulation remains the cornerstone of treatment, our understanding of the disease may allow enzyme replacement or gene therapy for a brighter future.

Renal disease is the most severe complication of IgA vasculitis. New treatments such as iptacopan and atrasentan are promising novel therapies for this challenging disease.

The C-reactive protein/albumin ratio (CAR) is a new measure for assessing disease severity and prognosis in inflammatory and neoplastic disorders. Dermatologists will increasingly encounter the CAR in daily practice.

Confluent and Reticulated Papillomatosis of Gougerot and Carteaud is usually seen in adolescents and young adults. The etiology of CARP remains to be determined, and further studies will judge its precise relationship to acanthosis nigricans.
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