DW Insights & Inquiries
![DW Insights & Inquiries header image](http://images.ctfassets.net/1ny4yoiyrqia/2rS1AsOc6UOSripY7MncMS/ff763e948c08e8de3cc626a729d0399b/Hero-New.png)
![Photo for DWII on Vasculitis on the run](http://images.ctfassets.net/1ny4yoiyrqia/1wuUzyy1ZKoHctUalWX64S/7f8d773f02f132e031f36c61a9a27f5c/Vasculitis-r2.png?w=450&h=300)
Vigorous exercise may induce a self-limited cutaneous leukocytoclastic vasculitis, including the recently described bilateral lower extremity inflammatory lymphedema.
![Image for DWII of fire ant stings on the skin](http://images.ctfassets.net/1ny4yoiyrqia/1HcLDH8ZZBhSp309YvFKsS/40c181f4a4e3d658269a5f1e7ad50cc2/Fire-ant-reactions-r2.jpg?w=450&h=300)
The fire ant venom, solenopsin (and its analogs), has demonstrated anti-inflammatory efficacy in mouse models of atopic dermatitis and psoriasis. Further research is necessary to determine its potential in human disease.
![Image for DWII on reducing medical errors in dermatology](http://images.ctfassets.net/1ny4yoiyrqia/hgG7J37v6FQxQhIsyWJn3/ba4feb55275aa32019ac138304a21179/DWII-Medical-Error-r1.jpg?w=450&h=300)
Although the overall error rate may be low, there are specific areas and opportunities to further reduce errors in the diagnostic pathway.
![Image for DWII on Advances in pruritus therapeutics](http://images.ctfassets.net/1ny4yoiyrqia/5RPKRIRKJmpWLWZiDid9up/5759b1cd373e1faaf381e0dd1e7d6006/Pruritus-r2.jpg?w=450&h=300)
Recent studies on the oral kappa-opioid receptor difelikefalin demonstrate benefit in treating pruritus in several dermatoses such as atopic dermatitis, notalgia paresthetica, and chronic kidney disease.
![Card illustration for CXCR4 antagonist therapy](http://images.ctfassets.net/1ny4yoiyrqia/44YfqCKbfFdxe6mwWuVZpW/af77317c6eedead425876cf255340d5e/CXCR4-Antagonist-Therapy-r2.jpg?w=450&h=300)
Advances in understanding the pathomechanisms of WHIM syndrome are the prelude to treating this syndrome — and other diseases — with CXCR4 antagonists.
![Image of nail changes for DWII on BAP1 tumor predisposition syndrome](http://images.ctfassets.net/1ny4yoiyrqia/5QDgo01D9yBlUBryJXWuUF/2ca35708968458e4f83cd03f13ab4697/USED_A_C-G__Ops_DERM_WORLD_DSC_2811-r2.jpg?w=450&h=300)
Patients with polydactylous onychopapillomas mandate evaluation for the BAP1-tumor predisposition syndrome.
To improve the practice of dermatology, while being stimulating, practical, thought-provoking, and enlightening by offering critical perspectives on current dermatologic literature meant to be used in the clinic today and in the future.
Explore Dermatology World Insights and Inquiries clinical topics by practice focus, condition, and medical journal source.