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DW Insights & Inquiries

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Photo for DWII on Vasculitis on the run
Vasculitis on the run

Vigorous exercise may induce a self-limited cutaneous leukocytoclastic vasculitis, including the recently described bilateral lower extremity inflammatory lymphedema.

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Fire ant stings: The therapeutic potential of solenopsin

The fire ant venom, solenopsin (and its analogs), has demonstrated anti-inflammatory efficacy in mouse models of atopic dermatitis and psoriasis. Further research is necessary to determine its potential in human disease.

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Pathway to reducing medical errors

Although the overall error rate may be low, there are specific areas and opportunities to further reduce errors in the diagnostic pathway.

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Advances in pruritus therapeutics: It’s Greek to us

Recent studies on the oral kappa-opioid receptor difelikefalin demonstrate benefit in treating pruritus in several dermatoses such as atopic dermatitis, notalgia paresthetica, and chronic kidney disease.

Card illustration for CXCR4 antagonist therapy
CXCR4 antagonist therapy based on a WHIM syndrome

Advances in understanding the pathomechanisms of WHIM syndrome are the prelude to treating this syndrome — and other diseases — with CXCR4 antagonists.

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BAP1 tumor predisposition syndrome

Patients with polydactylous onychopapillomas mandate evaluation for the BAP1-tumor predisposition syndrome.


The mission of DW Insights & Inquiries

To improve the practice of dermatology, while being stimulating, practical, thought-provoking, and enlightening by offering critical perspectives on current dermatologic literature meant to be used in the clinic today and in the future.

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