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DW Insights & Inquiries

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Image for DWII of skin showing signs of pellagra
Twenty-first century pellagra

Pellagra due to niacin deficiency still exists as a primary disorder in less developed countries and as a secondary disorder in industrialized countries.

Image for DWII of trichobacteriosis
Trichobacteriosis: A salute to the Shelleys

Trichobacteriosis is the more accurate name for the corynebacterial infection with the misnomer of trichomycosis axillaris.

Card image for DWII on Chanarin-Dorfman syndrome
Chanarin-Dorfman syndrome: Shifting out of neutral

Lipid vacuoles (Jordans’ anomaly) in white blood cells in patients with ichthyotic disorders (resembling nonbullous congenital erythroderma or the erythrokeratodermas) are indicative — but not pathognomonic — of the Chanarin-Dorfman syndrome.

Card image for DWII of a microscope slide of eccrine mucin-producing sweat gland carcinoma
Eccrine mucin-producing sweat gland carcinoma

Eccrine mucin-producing sweat gland carcinomas are low-grade malignancies that rarely metastasize. They are characterized by mucin and neuroendocrine markers. Immunostaining for insulinoma-associated protein 1 helps to secure the diagnosis.

Histology card image of squamoid eccrine ductal carcinoma
Squamoid eccrine ductal carcinoma

Squamoid eccrine ductal carcinomas may be highly aggressive malignancies characteristically observed on the head and neck of older men. Biopsies must be deep enough to ensure that these lesions are not diagnosed as squamous cell carcinomas.

Card image for DWII of cystic fibrosis sign on the skin
Further dermatologic observations in cystic fibrosis

The Cystic Fibrosis Dermatitis Arthritis Syndrome should be suspected in young (mostly female) cystic fibrosis patients presenting with episodic arthritis and rash.


The mission of DW Insights & Inquiries

To improve the practice of dermatology, while being stimulating, practical, thought-provoking, and enlightening by offering critical perspectives on current dermatologic literature meant to be used in the clinic today and in the future.

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