DW Insights & Inquiries
The aryl hydrocarbon receptor plays a key role in inflammation. Understanding its pathophysiology has led to new therapeutic agents such as tapinarof.
JAK inhibitors may cause weight gain. Although the precise pathomechanism is unknown, leptin dysregulation may be involved. Dermatologists must counsel patients treated with JAK inhibitors about the risk of weight gain.
Dermatologists may rarely encounter SMARCA4-deficient undifferentiated malignant neoplasms, either as primary cutaneous tumors or as metastatic lesions.
Toluene-2,5-diamine sulfate (PTDS) may be an allergen but may also be used as a substitute in some patients allergic to the hair dye paraphenylene diamine.
Spider angiomas are common lesions that may be secondary to underlying conditions, notably pregnancy or chronic liver disease. Topical timolol may be a valuable option for those who prefer a nonsurgical approach to therapy.
Erectile dysfunction (ED) is associated with chronic inflammatory disorders, including psoriasis, seborrheic dermatitis, hidradenitis suppurativa, atopic dermatitis, and others.
To improve the practice of dermatology, while being stimulating, practical, thought-provoking, and enlightening by offering critical perspectives on current dermatologic literature meant to be used in the clinic today and in the future.
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